An energy-based population-balance approach to model granule growth and breakage in high-shear wet granulation processes
نویسندگان
چکیده
منابع مشابه
A multi-compartment population balance model for high shear granulation
This work extends the granulation model published by Braumann et al. (2007) (Chemical Engineering Science, 62, 4717-4728) to include multiple compartments in order to account for mixture heterogeneity encountered in powder mixing processes. A stochastic weighted algorithm is adapted to solve the granulation model which includes simultaneous coalescence and breakage. Then, a new numerical method...
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ژورنال
عنوان ژورنال: AAPS PharmSciTech
سال: 2007
ISSN: 1530-9932
DOI: 10.1208/pt0803066